Heavy safes require sturdy foundations. Some are too heavy to have upstairs and could potentially bow your floors over the years. Corners are stronger.
I prefer to have things out of sight. Out of sight, out of mind. You're more likely to be ratted out or robbed by company employees doing service in your house or friends of employees and friends or friends of people that have been inside your home.
Neighbors watching you load your vehicle for a range day and have nothing better to do than tell every Tom, Dick, and Harry how many guns you walked out of your house with.
Years ago, my parents were burglarized during the half hour window of when my Dad left for work and when my Mom came home from her morning routines. People were watching and/or it was an inside job from my sisters shithead boyfriend at the time.