...The branches/sequels to those questions point me to wondering if there’s some genomic commonalities among those who have the various severe reactions. I’m sure there are, but then the questions become how likely is this to have occurred natively.
Just things I ponder.
IMHO, I don't think that's just your imagination.
The same thoughts had occured to me some time last year (pre-vax), based on people I know who got sick, and how bad, vs. those who didn't....It's still an open (amd evolving) question.